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The following compounds with higher antiallergic activities were isolated from eau de cologne mint leaves: 5,6,4′-trihydroxy-7,8-dimethoxyflavone (6), 5,6,4′-trihydroxy-7,8,3′-trimethoxyflavone (7), 5,6-dihydroxy-7,3′,4′-trimethoxyflavone (8), 5,6-dihydroxy-7,8,3′,4′-tetramethoxyflavone (9), and 5,6-dihydroxy-7,8,4′-trimethoxyflavone (10).The IC 50 values of compounds 6–10 against RBL-2H3...
The present study investigated the cytotoxicity of enhydrin (1), uvedalin (2) and sonchifolin (3) in cervical cancer cells. We have found that SLs 1–3 in doses in range of 0.22–10μM inhibited cell proliferation and induced apoptosis in both a dose- and time-dependent fashion. A significant cell death induction was supported by morphological studies. The apoptotic effect is associated with caspase-3/7...
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