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Inflammatory bowel disease (IBD) is an immunologically mediated disorder that is characterized by chronic, relapsing, and inflammatory responses. Dextran sulfate sodium (DSS)-induced experimental colitis in mice has been recognized as a useful model for human IBD and interleukin (IL)-1β is a key cytokine in the onset of IBD. The purpose of the present study was to clarify which pro-inflammatory mediators...
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