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Atrial tachycardias are the most common cardiac arrhythmias in clinical practice, which induce changes in atrial properties that help to perpetuate them. These changes are called “atrial remodeling”. Recent studies have shown that rapid ectopic activity principally on the pulmonary veins can trigger reentrant mechanisms and lead to atrial tachycardias. However, the influences of ectopic foci location,...
Structural remodeling plays an important role in the genesis and maintenance of atrial arrhythmias. In this work, the influence of atrial dilatation on the generation of reentrant activity trigger by an ectopic beat applied at different locations of the left atrium was studied. We have developed two 3D models of human atria: a model with electrical remodeling only, and a model with electrical and...
In this work, we have studied the different propagation patterns displayed in a human heart during acute ischemia. A 3-D geometrically and anatomically accurate regionally ischemic human heart was simulated. The ischemic region was located in the anterior side of the left ventricle mimicking the occlusion of the circumflex artery. Realistic heterogeneity and fiber anisotropy has been considered in...
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