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We improved our previous micro-device containing motile micro-algae (Euglena gracilis) cells for toxicity monitoring, by introducing micro-trenches between a micro-aquarium and two surrounding channels. Target test solution was introduced from the bypass channel to the micro-aquarium through micro-trenches, with a pulse injection and continuous diffusion. Although the chemical gradient formed in the...
We developed and examined a toxicity sensing microchip, where 200-300 cells of flagellated microbes (Euglena gracilis) were placed and their movements were monitored with a video camera. The microchip had two microchannels for test sample and reference flow, and the cells were confined completely in a separated closed-space (micro-aquarium). The two microchannels run aside of the micro-aquarium, and...
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