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1. One of the major causes of metabolic syndrome is elevated 11β‐hydroxysteroid dehydrogenase 1 (11β‐HSD1) in the liver and adipose tissue. High 11β‐HSD1 expression contributes significantly to the diabetic phenotype in db/db mice. The purpose of the present study was to test the effect of the pharmacological inhibition of 11β‐HSD1 inhibition by carbenoxolone in db/db mice, a genetic model of diabetes...
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