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The extensive modification of Plasmodium falciparum‐infected erythrocytes by variant surface antigens plays a major role in immune evasion and malaria‐induced pathology. Here, using high‐resolution microscopy, we visualize the spatio‐temporal expression dynamics of STEVOR, an important variant surface antigens family, in a stage‐dependent manner. We demonstrate that it is exported to the cell surface...
Gametocyte maturation in Plasmodium falciparum is a critical step in the transmission of malaria. While the majority of parasites proliferate asexually in red blood cells, a small fraction of parasites undergo sexual conversion and mature over 2 weeks to become competent for transmission to a mosquito vector. Immature gametocytes sequester in deep tissues while mature stages must be able to circulate,...
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