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Vesicle Assemblies with DNA Nanorulers
In article number 2308344, Min Li, Xiaolei Zuo, and co‐workers used synthetic vesicles and DNA nanorulers to reconstruct in vitro the vesicle assemblies that mimic vesicle clusters in living cells. They demonstrate the amperometric monitoring of vesicle assemblies using nanoelectrode with high precision. The further application in vivo enables to analyze the...
Nanoscale vesicles such as synaptic vesicles play a pivotal role in efficient interneuronal communications in vivo. However, the coexistence of single vesicle and vesicle clusters in living cells increases the heterogeneity of vesicle populations, which largely complicates the quantitative analysis of the vesicles. The high spatiotemporal monitoring of vesicle assemblies is currently incompletely...
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