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Objective
Periodontitis is one the most common chronic inflammatory conditions, resulting in destruction of tooth‐supporting tissues and leading to tooth loss. Porphyromonas gingivalis activates host macrophages to secrete pro‐inflammatory cytokines and elicit tissue damage, in part by inducing NF‐kappa‐B transactivation. Since NFκB transactivation is negatively regulated by the Nicotinamide adenine...
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