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Abstract Homologous recombination in Saccharomyces cerevisiae and other organisms can be stimulated by transcription. Consistent with this, we find that recombination of a chromosomal ade1 allele with a plasmid-borne ADE1 ORF under the control of the GAL1 promoter increased from 6.1106 to 1.7104 when transcription of the plasmid locus was induced by growing the cells in the presence of galactose....
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