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A unique biomimetic drug‐delivery system composed of 4T1‐breast‐cancer‐cell membranes and paclitaxel‐loaded polymeric nanoparticles (PPNs) (cell‐membrane‐coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell‐specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung...
Limited blood circulation and poor tumor penetration are two main obstacles hampering the clinical translation of conventional nanosized drug delivery systems (NDDS). Here, red‐blood‐cell (RBC)‐mimetic nanoparticles (NPs) with long circulation and peptide‐enhanced tumor penetration for treating metastatic breast cancer are reported. The RBC‐mimetic NPs are composed of a paclitaxel (PTX)‐loaded polymeric...
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