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Purpose:To determine the relationship between changes in the extracellular matrix (ECM) and T1ρ and T2 values in vivo. The ECM is composed of proteoglycan (PG), collagen, and water. It has been unclear which of the ECM constituents affects T1ρ and T2 mapping in living human cartilage.
Materials and Methods:Sagittal T1ρ and T2 maps were preoperatively obtained from 20 knee osteoarthritis patients...
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