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Low compliance with medication is the major cause of poor outcome in schizophrenia treatment. While surgically implantable solvent‐cast pellets were produced to improve outcome by increased compliance with medication, this process is laborious and time‐consuming, inhibiting its broader application (Siegel et al., Eur J Pharm Biopharm 2006;64:287–293). In this study, the previous fabrication process...
Non-adherence with medication remains a major correctable cause for poor outcome in schizophrenia. We describe a surgically implantable preparation of haloperidol with the aim that patients will have superior outcomes with improved medication adherence from implants. In contrast to depot formulations, implantable pellets could last many months, providing symptomatic improvement for periods of time...
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