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Abstract. The proteins nCL-2 and nCL-2 are members of the Ca2+-dependent cysteine protease (calpain) superfamily, with stomach-specific expression. Like other typical calpains, nCL-2 has three distinct domains, a protease, a C2-like, and a 5EF-hand Ca2+-binding domain, as well as the N-terminal propeptide region. On the other hand, nCL-2 lacks the C2-like and 5EF-hand domains but is otherwise identical...
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