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The objective of this study was to prepare and characterize chitosan–magnesium aluminum silicate (CS–MAS) nanocomposite films as a buccal delivery system for nicotine (NCT). The effects of the CS–MAS ratio on the physicochemical properties, release and permeation, as well as on the mucoadhesive properties, were investigated. Molecular interactions between the components of the film were also investigated...
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