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From a dichloromethane extract of Newbouldia laevis roots, four new (6-hydroxydehydroiso-α-lapachone, 7-hydroxydehydroiso-α-lapachone, 5,7-dihydroxydehydroiso-α-lapachone and 3-hydroxy-5-methoxy-dehydroiso-α-lapachone) and six known naphthoquinones have been isolated. Their structures were established by spectroscopic methods (UV, EI mass spectrometry, 1 H and 13 C NMR) and that...
A dichloromethane extract of the roots of Eriosema tuberosum exhibited antifungal activity againstCladosporium cucumerinum and Candida albicans using TLC bioautography. Bioassay-directed fractionation led to the isolation of four new compounds, eriosemaones A-D, together with a known compound, flemichin-D, as the active constituents. Three inactive polyphenols were also isolated after methylation,...
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