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This work reports on fully integrated “sample‐in‐signal‐out” microfluidic paper‐based analytical devices (μPADs) relying on bioluminescence resonance energy transfer (BRET) switches for analyte recognition and colorimetric signal generation. The devices use BRET‐based antibody sensing proteins integrated into vertically assembled layers of functionalized paper, and their design enables sample volume‐independent...
Der Nachweis von Antikörpern im Blut ist denkbar einfach. In ihrer Zuschrift auf S. 15595 ff. integrieren D. Citterio, M. Merkx et al. auf Antikörper abzielende biolumineszierende Sensorproteine und andere essenzielle Testkomponenten in ein Analysegerät mit papierbasiertem Mikrofluidiksystem. Ein Blutstropfen, eine Digitalkamera und zwanzig Minuten Zeit sind ansonsten alles, was benötigt wird, um...
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