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Protein design provides an attractive approach to test the essential features required for folding and function. Previously, we described the design and structural characterization in solution of mimochromes, a series of miniaturized metalloproteins, patterned after the F-helix of the hemoglobin β-chain. Mimochromes consist of two medium-sized helical peptides, covalently linked to the deuteroporphyrin...
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