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Aversion to novel food items was studied in male rats and mice after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure using chocolate consumption as an indicator. The correlation of this phenomenon with susceptibility to acute toxicity and CYP1A1 induction was examined by determining the dose–response of chocolate aversion in differently dioxin-sensitive rat lines after TCDD (0.01–10μg/kg). Furthermore,...
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