The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Inflammatory Bowel Disease Relief
In article number 2214693, Yunjiao Zhang and co‐workers demonstrate 2D cobalt oxyhydroxide nanosheets (Co NSs) with excellent multienzyme‐like activity as potential inhibitors of NLRP3 inflammasome and pyroptosis. Owing to the robust reactive oxygen species scavenging and oligomerization inhibiting ability, Co NSs block the assembly and activation of NLRP3 inflammasome,...
Nucleotide‐binding domain and leucine rich repeat family pyrin domain containing 3 (NLRP3) inflammasomes are implicated in diverse inflammatory diseases, so their activation needs to be tightly controlled. Over generation of reactive oxygen species (ROS) is a key factor in NLRP3 inflammasome activation. Consequently, nanozymes with ROS scavenging ability are potential inhibitors of NLRP3 activation...