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Seven different ferrocene derivatives have been tested in vitro against Ehrlich ascites tumor cells. Neither ferrocene nor the monosubstituted derivative N,N-dimethylaminomethylferrocene showed cytotoxic activity (IC 50 >1000μM for 3h treatments). Better results were obtained with 1,2-disubstituted derivatives. The IC 50 values ranged from 376.6μM for 1,2-diformylferrocene to 71...
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