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Galanin-like peptide (GALP) is a 60 amino-acid peptide, and the GALP mRNA is restricted to pituicytes in the posterior pituitary gland (PP) and neurons in the hypothalamic arcuate nucleus (Arc). We examined whether the GALP gene expression in the PP and Arc would be induced after intraperitoneal (i.p.) administration of hypertonic saline, that is, acute osmotic stimulus, in rats. The dose–response...
The effects of water deprivation and chronic salt loading on the expression of the brain-derived neurotrophic factor (BDNF) gene were examined in the rat subfornical organ (SFO), using immunohistochemistry for BDNF and in situ hybridization histochemistry. Increased BDNF-like immunoreactivity was observed in the SFO after water deprivation for 4 days. Water deprivation for 24 h and 2 and 4 days and...
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