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We retrospectively evaluated the imaging spectrum of Pelizaeus–Merzbacher disease (PMD) in correlation with the clinical course and genetic abnormality.We collected the magnetic resonance imaging (MRI) findings of 19 genetically proven PMD patients (all males, aged 0–29years old) using our integrated web-based MRI data collection system from 14 hospitals. The patterns of hypomyelination were determined...
Objectives To evaluate the outcome of West syndrome and to elucidate the differences in the outcome related to the timing of brain injury.Study design Medical records of 60 patients who were followed regularly for more than seven years were reviewed. The following clinical features were assessed: onset, seizure evolution, electroencephalography and intelligence. Those variables were compared among...
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