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Bone marrow hemophagocytosis is a frequently observed but not mandatory finding for the diagnosis of hemophagocytic lymphohistiocytosis (HLH). However, the impact of bone marrow hemophagocytosis on the diagnosis of HLH is still not clear in adult patients. Thus, we retrospectively analyzed adult patients with bone marrow hemophagocytosis between 2000 and 2014 to determine its clinical significance...
BackgroundMolecular detection of tyrosine hydroxylase (TH) transcripts by quantitative RT‐PCR (qRT‐PCR) is a sensitive method to detect neuroblastoma (NB) cells in the bone marrow (BM). However, its clinical utility following chemotherapy has not been thoroughly investigated.
ProceduresTH transcripts in the BM were measured by qRT‐PCR both at diagnosis and during the course of chemotherapy. The results...
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