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The mammalian reovirus σ1 protein is responsible for viral attachment to host cells and hemagglutination properties of the virus. In the present study, sequence similarity between σ1 and chicken-type lysozymes prompted us to investigate additional functions of the σ1 protein. Expression in Pichia pastoris yeast cells showed that σ1 can actually cleave lysozyme substrates, including complex sugars...
In the present study, computer-assisted searches for sequence similarities were performed with amino acid sequences from mammalian reovirus proteins. These analysis revealed that many proteins of reovirus are partially similar to known viral or cellular proteins. Consensus sequences have been identified that are in accordance with already suspected functions of reovirus proteins. The analysis has...
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