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Objective: To investigate the arrangement of chromosomes within pronuclei-stage mouse zygotes.Design: In vitro study.Setting: Academic medical center.Patient(s): None.Intervention(s): None.Main Outcome Measure(s): Location of major α-satellite DNA, centromeres, and telomeres, and relative location of chromosomes.Result(s): Chromosomes appeared to be oriented inward by centromeres and to be interconnected...
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