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Polyenes are important for vision in all sighted species. The visual pigments (the rhodopsins) all use 11-cis-retinal as the chromophore; some possible reasons for the importance of this isomer are now emerging. New results on the involvement of xanthophils in the maintenance of the retina are also discussed.
Background: Aminoglycoside antibiotics interfere with ribosomal protein synthesis and with intron splicing. Various lines of evidence suggest that RNA is the molecular target for amino glycosides, but little is known about the recognition process. Is recognition of a particular aminoglycoside specific for certain RNA structures? If so, what are the rules for recognition? We have begun to investigate...
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