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The crystal structure of a hypothetical protein, TM1457, from Thermotoga maritima has been determined at 2.0Å resolution. TM1457 belongs to the DUF464 family (57 members) for which there is no known function. The structure shows that it is composed of two helices in contact with one side of a five-stranded β-sheet. Two identical monomers form a pseudo-dimer in the asymmetric unit. There is a large...
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