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The near N-terminal region of chromogranin A (CGA) has been shown to be the secretory vesicle membrane binding region, and tetrameric chromogranin A has been demonstrated to bind four molecules of an intraluminal loop peptide of the inositol 1,4,5-trisphosphate (IP 3 ) receptor. It was therefore necessary to determine whether the conserved near N-terminal region of CGA interacts with the intraluminal...
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