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The present study was designed to examine whether noradrenergic projections from the A1 cell group in the ventrolateral medulla to the median preoptic nucleus (MnPO) transmit information from the peripheral baroreceptors. In urethane-anesthetized male rats, extracellular concentrations of noradrenaline (NA) in the region of the MnPO in response to hemorrhage (5 or 10ml/kg) were monitored with in vivo...
Electrical stimulation of the A1 noradrenergic region of the ventrolateral medulla produced synatic excitation (n=19, 9%), inhibition (n=5, 2%) or no effect (n=184, 89%) in the activity of a total of 208 neurons in the subfornical organ (SFO) in male rats under urethane anesthesia. Almost all (n=18) of the excitatory responses (n=19) were blocked by microiontophoretically-applied phentolamine, an...
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