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In article number 1909285, Yong Liu, Xiangyang Shi, and co‐workers report hypoxia‐targeted dendrimer‐based nanodevices, which can be employed as a contrast agent for dual mode CT/MR imaging of hypoxic tumors. Moreover, under X‐ray irradiation, the developed nanohybrids enable enhanced reactive oxygen species production, promote DNA damage, and prevent DNA repair, facilitating sensitized radiotherapy...
The efficacy of radiation therapy (RT) is often limited by the poor response of hypoxia inside most solid tumors. The development of a theranostic nanoplatform for precision‐imaging‐guided sensitized RT for tumor hypoxia is still challenging. Herein, the creation of hypoxia‐targeted dendrimer‐entrapped gold nanoparticles complexed with gadolinium(III) (Gd‐Au DENPs‐Nit) for dual‐mode CT/MR imaging...
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