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Metabolism in microbial colonies responds to competing species, rapidly evolving genetic makeup, and sometimes dramatic environmental changes. Conventional characterization of the existing and emerging microbial strains and their interactions with antimicrobial agents, e.g., the Kirby–Bauer susceptibility test, relies on time consuming methods with limited ability to discern the molecular mechanism...
Visualisierung der Interaktionszone: Dass Mikroben Resistenzen gegen Antibiotika entwickeln, ist ein ernstes Problem bei der Behandlung von Infektionskrankheiten. In der Zuschrift auf S. 15259 ff. beschreiben A. Vertes et al. die Anwendung von Laserablation mit Elektrosprayionisation (LAESI) in Kombination mit Massenspektrometrie (MS), um Einblicke in die Wechselwirkungen zwischen Mikroben und Antibiotika...
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