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In this work the isopycnic method to construct kinetic plots for SFC was used to investigate the performance limits of an SFC system when using sub-2µm fully porous particles and sub-3µm superficially porous (core–shell) particles. This isopycnic kinetic plot method for SFC was developed and tested earlier for SFC separations on native silica with pure CO 2 as mobile phase. In the current...
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