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A biosensor scheme that employs long range surface plasmons (LRSPs) for the efficient excitation and collection of fluorescence light from fluorophore-labeled biomolecules captured in a three-dimensional hydrogel matrix is discussed. This new approach to plasmon-enhanced fluorescence (PEF) is experimentally and theoretically investigated by using the Kretschmann configuration of attenuated total reflection...
An implementation of evanescent wave affinity biosensor with a large-capacity three-dimensional binding matrix for ultra-sensitive detection of molecular analytes is investigated. In the experimental part of the work, highly swollen carboxylated poly(N-isopropylacryamide) (NIPAAm) hydrogel with up to micrometer thickness was grafted to a sensor surface, functionalized with antibody recognition elements...
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