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A novel label-free biosensor based on the measurement of binding-induced refractive index changes by hydrogel optical waveguide spectroscopy (HOWS) is reported. This biosensor is implemented by using a surface plasmon resonance (SPR) optical setup in which a carboxylated poly(N-isoproprylacrylamide) (PNIPAAm) hydrogel film is attached on a metallic surface and modified by protein catcher molecules...
The kinetics of moisture sorption/desorption in poly(terephthalate-co-phosphate) thin films was investigated in situ at T=25°C using optical waveguide spectroscopy (OWS). At low water activities, Fickian diffusion was observed for the initial phase of the sorption process, while at high activities, due to the clustering of water, a complex sorption behavior was found. The moisture sorption isotherms...
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