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Viruses are devastating pathogens of humans, animals, and plants and virus infection mechanism is an important subject of virology and pathology research. To further our understanding of how viruses use the resource of infected cells, we systematically tested virus-yeast PPI network for the effect of virus perturbation on host proteins. Two viruses used in our study interact with vastly different...
Hepatitis B virus (HBV) infected people are at high risk of death from cirrhosis of the liver and liver cancer. To overcome the drug-resistant challenge of current anti-HBV compounds, substances blocking host support proteins in HBV infection are becoming increasingly important. Comprehensive HBV-human interactome map, which describe gene-level interactions of HBV proteins with human proteins, may...
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