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Animals' perception and behavior involve integration of multiple sensory modalities. Caenorhabditis elegans is a useful model for studying multimodal sensory integration, as it has well‐characterized neuronal circuits in a relatively simple nervous system. However, most studies based on functional imaging have only been conducted on single modal stimuli, because well‐controlled multimodal experiments...
In article number 1905852, Hang Lu and co‐workers develop a microfluidic platform that can deliver spatially and temporally controlled multi‐modal stimuli to C. elegans to study multisensory integration in the brain. The cover depicts the nematode being stimulated by mechanical and chemical cues in the device; the nervous system integrates these stimuli to generate behavioral outputs—forward, backward,...
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