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Thoreliolides A and B, two new polyisoprenylated benzoylphloroglucinol derivatives with a novel carbon skeleton, together with four known compounds, were isolated from the fruits of Calophyllum thorelii and their structures elucidated using spectroscopic methods. Thoreliolide B showed moderate activity against three cancer cell lines, MCF-7, HeLa and NCI-H460, with IC50 values of 9.7, 16.6 and 24...
Two new polyisoprenylated acylphloroglucinols, thoreliones A and B, and a new polyisoprenylated tetracyclic xanthone, oxy-thorelione A, together with twelve known compounds, were isolated from the bark of Calophyllum thorelii. The new structures were determined using spectroscopic methods and chemical modification. The major compound thorelione A (1) showed moderate cytotoxic activity against MCF-7,...
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