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The development of adaptive immune responses against infectious agents relies on the initiation of antigen specific immune responses in secondary lymphoid organs and on the migration of effector cells at the site of infection. Similarly, the development of anti-tumor immunity depends on the recognition of tumor-derived antigens by specific lymphocytes in the context of the lymphoid tissues and on...
The pivotal role of CD8 + T cells in the immune response to Toxoplasma gondii infection had been confirmed within the last years. Recent reports claim in addition an important role of B cells, as antigen presenting or costimulation providing cells, in the immunization of cytotoxic T cells. To figure out a possible function of B cells in the triggering of the immune response in an experimental...
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