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ObjectiveWe studied whether suppressed secretion of the orexigenic peptide ghrelin might be involved in the anorexigenic effects of nicotine.
MethodsFifty healthy non‐smokers chewed gums containing 2 mg nicotine, or no nicotine in a double‐blind randomised crossover design in two independent studies.
ResultsPlasma nonacylated ghrelin was not significantly affected by nicotine after 30 and 60 min....
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