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While fixed point dynamics is still the predominant regime used for information processing, recent brain observations and computational results suggest more and more the importance/necessity to include and rely on more complex dynamics. Independently, since their introduction sixty years ago, cell assemblies are still a powerful substrate for brain information processing. Here, the first part of this...
Parallel and sequential manipulation of trapping, labeling and content extraction of single cell was realized using a 2-D simple flow channels. The proposed system consists of main channels, cell trapping pockets, drain channels and single cell content collection channels. We fabricated prototypes having 16 cell trapping pockets and 512 cell trapping pockets. Sequential all single cell handling for...
Many cognitive tasks require the ability to maintain and manipulate simultaneously several chunks of information. Numerous neurobiological observations have reported that this ability, known as the working memory, is strongly associated with the activity of the prefrontal cortex. Furthermore, during resting state, the spontaneous activity of the cortex exhibits exquisite spatiotemporal patterns sharing...
Thirty years ago, hippocampal cells firing at selective location in the environment were discovered, with a major impact in our understanding of memory formation. Recently, "grid cells", firing when the rat is located at any of the vertices of grid fields covering the environment, have been discovered in the medial enthorinal cortex. These cells are supposed to be responsible for the organization...
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