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Bloating and gas are frequent complaints in the gastrointestinal clinic, yet they are poorly understood and managed. Recently, there has been significant new knowledge regarding the etiology and treatment of these conditions. They are caused by a heterogeneous group of disorders that include dietary intolerances such as lactose, fructose or fructan, infections such as small intestinal bacterial or...
Transient lower oesophageal sphincter relaxations (TLOSRs) occur frequently and are the main mechanism of acid reflux. The only means of currently detecting TLOSRs is intra-luminal manometry and the probes themselves may stimulate TLOSRs. The squamo-columnar junction moves 4–5 centimeters proximally during TLOSRs and this provides a means of detecting such episodes. The objective of this work is to...
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