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The major neuronal gap junction protein connexin36 (Cx36) exhibits the remarkable property of “run-up”, in which junctional conductance typically increases by 10-fold or more within 5–10min following cell break-in with patch pipettes. Such conductance “run-up” is a unique property of Cx36, as it has not been seen in cell pairs expressing other connexins. Because of the recent observation describing...
Trypanosoma cruzi and Toxoplasma gondii are protozoan parasites capable of causing infections of the nervous system. In order to determine effects of infection by these organisms on intercellular communication in the brain, dye coupling and connexin abundance and distribution were examined in leptomeningeal cells and astrocytes infected with T. cruzi or T. gondii. For both cell types infected with...
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