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Previous studies have identified effects of age and vascular risk factors on brain injury in elderly individuals. We aimed to establish whether the effects of high blood pressure in the brain are evident as early as the fifth decade of life. In an investigation of the third generation of the Framingham Heart Study, we approached all participants in 2009 to ask whether they would be willing to undergo...
The main neurological causes of morbidity and mortality are stroke and dementia. We contend that the most relevant and readily communicated risk estimate for stroke and dementia is lifetime risk, which is the probability of someone of a given age and sex developing a condition during their remaining lifespan. Lifetime risk estimates describe the population burden; however, they can be refined with...
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