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The fourth member of the β 2 -integrin family of adhesion molecules, CD11d (α D β 2 ), is expressed on a wide variety of immune cells, however its function in autoimmune diseases, including EAE remains unknown. We induced EAE in wild-type and CD11d −/− C57BL/6 mice using myelin oligodendrocyte glycoprotein (MOG 35–55 ) peptide. The clinical course and histopathology...
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