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Objective
Theophylline is a phosphodiesterase inhibitor that is being used clinically for asthma therapy. In addition, it is recognized as a cosmetic agent with possible anti‐ageing and anti‐oxidative properties. Nevertheless, how it affects human skin is still poorly examined.
Methods
Theophylline (10 or 100 µM) was administered to the culture medium of full‐thickness human skin ex vivo for 24...
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