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BackgroundFarm exposure has been shown to protect from childhood asthma and allergic diseases, but underlying immunological mechanisms are not clear yet.
ObjectiveTo explore whether farming lifestyle determines cytokine profile of peripheral blood mononuclear cells (PBMCs) of 4.5‐year‐old children (n = 88) from the Finnish PASTURE birth cohort study.
MethodsWe analysed regulatory (IL‐10, IL‐2),...
Background
Gut microbiota and intestinal inflammation regulate the development of immune‐mediated diseases, such as allergies. Fecal calprotectin is a biomarker of intestinal inflammation.
Objective
We evaluated the association of early‐age fecal calprotectin levels to the later development of allergic diseases in children from farming and non‐farming environments and further studied the effect...
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