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Background: Although the demonstration of leptomeningeal dissemination is the most important predictor of poor outcome in children with medulloblastoma, there is lack of consensus on the prognostic value of a positive cerebrospinal fluid (CSF) cytology (i.e., stage M1). Patients and methods: Eighty-six pediatric medulloblastoma patients treated in Switzerland between 1972–1991 were retrospectively...
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