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BackgroundOf the Rh blood type, Del is a rare variant that elicits the weakest anti‐D reactivity. In this study, we revisit the genetic changes of Del allele and characterise the RHD splicing transcripts to realise the molecular basis of Del formation in the Taiwanese population.
Study design and methodsThe RHD exons from Del and D‐positive individuals were amplified by polymerase chain reaction...
Background and ObjectivesAel is a rare blood type that is characterized by weak agglutination of RBCs when reacts with anti‐A antibody in adsorption–elution test. Although IVS6 + 5G→A mutation is known to associate with the Ael blood type, genetic and mechanistic evaluation for the weak agglutination of Ael with IVS6 + 5G→A mutation has not yet been completely addressed.
Materials and MethodsIn this...
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