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Recent analyses of collagen, elastin and fibronectin matrix assembly, organization and remodeling have been facilitated by the use of tagged proteins that can be visualized without the need for antibody labeling. Here, we report the generation of C-terminal tagged, full-length and “processed” (α3ΔLG4–5) human α3 as well as C-terminal tagged, full-length human β3 laminin subunits in adenoviral vectors...
A simplification of the laminin nomenclature is presented. Laminins are multidomain heterotrimers composed of α, β and γ chains. Previously, laminin trimers were numbered with Arabic numerals in the order discovered, that is laminins-1 to -5. We introduce a new identification system for a trimer using three Arabic numerals, based on the α, β and γ chain numbers. For example, the laminin with the chain...
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