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Die Frage nach dem Stellenwert der primären Hochdosischemotherapie bei Patienten mit metastasiertem Keimzelltumor kann derzeit trotz Vorliegen zweier randomisierter Studien (eine zur primären Hochdosistherapie, eine zum Einsatz einer Hochdosischemotherapie im Rezidiv) mit negativem Ausgang nicht eindeutig beantwortet werden. Für Patienten mit „poor prognosis“ ohne vorherige Behandlung sind die Ergebnisse...
The aim of this study was to identify treatment strategies and therapeutic or clinical factors that predict for response to salvage therapy and survival in patients with metastatic ‘Indiana advanced’ or International Germ-Cell Cancer Collaborative Group (IGCCCG) poor prognosis’ germ cell cancer (GCT) failing first-line sequential high-dose chemotherapy plus autologous stem cell support (HD-CT). A...
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